South of Pendleton, this unit has mule deer, elk and a few whitetail deer. It varies from desert flats and foothills to forested mountains in the Umatilla National Forest, including the North Fork John Day Wilderness in the southeastern corner.

Mature bucks and bulls can be hard to find in this unit because hunting pressure is often intense near roads and sometimes away from roads. Hunters who hike into secluded canyons or have access to private land have a fair chance of finding good bull elk and buck deer.