Hunters have found Unit 66 - Malheur River in Oregon to be a challenging yet rewarding area with diverse terrain. Key insights include the necessity of understanding the seasonal movement patterns of game, such as elk and deer, due to the distinct landscape features and availability of water sources. Draw odds can be competitive, so persistent scouting and pre-season preparation are highly recommended. Hunters advise paying close attention to weather conditions, as they significantly impact game behavior and movement within the unit.