Hunters discussing Unit 45A in Arizona emphasize the area's rugged terrain and the need for physical preparation, highlighting the unit's challenges but also its rewards for those willing to put in the effort. Many recommend scouting trips prior to the season opener to familiarize with game patterns, and suggest focusing on water sources as potential hotspots given the unit's arid climate. There is a consensus that understanding the movement of herds through the canyons and flatlands is crucial, with several expressing success during the early and late hunting seasons when game is more active. Overall, Unit 45A is portrayed as a demanding yet potentially fruitful area for prepared and dedicated hunters.