Area 121 in Wyoming makes up part of the western edge of the Big Horn basin. The northern border of the unit forms the state line with Montana, the western edge running south towards the town of Cody. Heart Mountain looms tall over the landscape in an otherwise low elevation, desert like area. At the east face of the Beartooth Mountains, this area is the edge transition from high mountains to lower broken country stretching out to the east. This area is a general unit for both species of deer and offers a wide variety of terrain and challenges to hunters wanting a true western experience.For nonresidents, this area is part of Region X and tags drawn for this area are also valid in: 122, 123, 124, 127

While a few true trophy deer are taken in this area each year, with generally arid conditions, vast landscape and an active resident hunting population, older age class bucks can be very challenging to find here.